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Report

Beyond the Prescription: Community Pharmacy's Role in Comprehensive GLP-1 Care

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As demand for glucagon-like peptide-1 (GLP-1) therapies grows and indications expand across chronic disease, people face a fragmented landscape: coverage restrictions, affordability challenges, side effects, lifestyle changes, and adherence barriers. Recent developments, including the Medicare GLP-1 Bridge demonstration, show how quickly access is shifting for some populations, yet raise questions about how to ensure people are comprehensively supported. Because obesity and related cardiometabolic conditions are multifactorial and chronic in nature, GLP-1 care requires sustained management rather than a single point of intervention. Community pharmacies can play a pivotal role in helping people use these treatments safely and successfully over time. Initiating therapy is the first step in a process that typically requires dose titration, side- effect management, adherence support, lifestyle changes, and coordination among prescribers and health plans.

To examine this opportunity, Milken Institute Public Health analyzed how community pharmacies can support people throughout their GLP-1 journey. The research draws on thought-leader interviews with pharmacies, advocacy organizations, payers, and pharmaceutical manufacturers, along with complementary public opinion research, to better understand key gaps and opportunities in the comprehensive cardiometabolic care pathway, pharmacists’ role in supporting this pathway, and patient perceptions of pharmacists as care partners.

Four themes emerged from this research:

1) pharmacy as the ongoing, low-barrier touchpoint in GLP-1 care;
2) integration with wraparound care and personalized support;
3) navigating access friction, from “Bridge” to what comes next; and
4) the systems and infrastructure constraints that limit consistent delivery.

Together, these highlight opportunities to strengthen how pharmacies can support the full GLP-1 care continuum. The report recommends actions that pharmacies, payers and health plans, patients and consumers, government and policymakers, and prescribing providers can take to establish a more consistent role for pharmacy in wraparound GLP-1 care.