Community-Based Research Infrastructure

Enabling Networks of Research Infrastructure for Community Health Through Clinical Trials (ENRICH-CT)

Overview

FasterCures is dedicated to promoting collaboration between the public and private sectors to enhance the infrastructure for inclusive clinical research in the US. To meet this need, we are leading ENRICH-CT, a multistakeholder group comprising business, government, and nonprofit leaders.

ENRICH-CT serves as a precompetitive initiative to share best practices, support collective action on common challenges, and build an ecosystem of excellence that sustains the workforce, partnerships, resourcing, and technology needed to effectively conduct research closer to communities.

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About the Program

The Milken Institute’s FasterCures is leading Enabling Networks of Research Infrastructure for Community Health through Clinical Trials (ENRICH-CT), a multi-stakeholder initiative focused on driving dialogue and advancing practical solutions for ways the public and private sectors can support more infrastructure in the US for more inclusive clinical research.

ENRICH-CT’s Objectives

  • Develop and advance solutions by creating resources and recommending tools, policies, and practices to strengthen community research infrastructure
  • Convene and connect diverse stakeholders to exchange ideas and elevate best practices
  • Build capacity and sustainability through knowledge sharing, mentorship, and cross-sector learning to bring research closer to communities and support long-term infrastructure 
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ENRICH-CT's Focus Areas

Connecting to Share Information
Offering an opportunity to collaborate and exchange ideas pre-competitively and to learn about experiences and innovative developments from a cross-sector coalition.
Elevating Policy and Practice Change
Both through formal policy recommendations and informally in small, actionable steps that begin the path to a national clinical research infrastructure and serve the needs of the future, demographically diverse population of the US.
Addressing Burden at the Front Lines
Identifying areas where common practices add unnecessary burden to sites and community partners and opportunities to support those newer to community engagement or to clinical research with an "on-ramp" to success.

How ENRICH-CT Works

Working Groups Continued

This work will identify key enabling principles that broaden research participation, reduce barriers, deliver meaningful benefits to communities, and make research participation within routine clinical practice attainable. Research stakeholders interested in bringing clinical research closer to communities will be able to identify the policies and policy actors that are affecting their ability to do so, and exercise existing opportunities and flexibilities more readily. The research ecosystem will be able to identify and prioritize areas in need of alignment or action, and advocate for policies and practices that support the guiding enabling principles.  

This working group focuses on how to best reduce burden in the lifecycle of a site by determining areas of highest burden for sites and sponsors, mapping existing site selection and study startup processes, collating resources and identifying areas for collective action where few solutions exist.  This resource will identify ways to integrate newer sites and investigators into the research process in fundamentally different, flexible ways. 

This working group will seek to strengthen the role of community-serving organizations in clinical research by developing sustainable business models that support long-term, equitable research collaborations and partnerships. The business model design will be a critical resource for CSOs, funders, researchers, and policymakers seeking to build more durable, inclusive, and community-anchored research ecosystems.  

ENRICH-CT’s Members

2026 ENRICH-CT Members

The ENRICH-CT coalition has unique reach due to its diverse membership:  

Community Impact
Coalition members engage broad and historically underrepresented populations, including rural populations, under- or uninsured populations, African Americans, Asian and Pacific Islanders, and Hispanic communities across the United States.
Data at Scale
The Coalition includes leading EHR platforms with upwards of half a billion users, and members who steward billions of de-identified patient records, providing real-world insights essential to improving our clinical research ecosystem.
R&D Leadership
ENRICH-CT includes global pharmaceutical companies investing tens of billions of dollars in R&D budget annually, as well as CROs and other organizations that operationalize clinical trials, supporting the full spectrum of research.
Access Where You Are
Health systems involved in ENRICH-CT are embedded across the country and collectively reach tens of millions of patients, conduct tens of thousands of studies with hundreds of thousands of participants at any given time. Its membership also includes large retailers who are helping extend the reach of clinical trials to every corner of the US. In addition, the coalition includes digital health and decentralized trial platforms that collectively enable research across millions of patients, expanding access to patients who may not live near traditional research centers.

Landscape Inventory

The landscape inventory is a collection of initiatives related to ENRICH-CT's goal of advancing community-based clinical research, especially those spearheaded by coalition members. The resource serves as a method to track the state of the ecosystem, prioritize areas of need, and avoid redundant efforts. The document will be updated periodically as additional initiatives are developed, identified, and submitted. To request the landscape inventory, please email [email protected].

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For more information about partnering with us, please contact us at [email protected].

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