As the world becomes increasingly developed and urbanized, finding ways in which cities can become more livable, sustainable, and digitally enabled is a growing global challenge. In addition, global cities, including their infrastructure networks, face numerous challenges from climate change, including adapting to sea level rises, global heating, and natural disasters such as floods, fires, and tropical storms. This panel will share perspectives from different cities across the globe, focusing on developing resilient infrastructure networks, adapting to climate risks, and using digital tools to improve the built environment for their inhabitants.