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Despite significant advances in cancer prevention, diagnosis, and treatment, inequities in the quality of, and access to care continue to drive disparate outcomes throughout Asia-Pacific and the Middle East. Addressing these challenges will require sustained collaboration across governments, health systems, industry, civil society, and the communities most affected. This invitation-only roundtable will bring together senior leaders from across the cancer-care ecosystem to examine how public-private partnerships can promote early detection and screening. The discussion will also explore specific regional challenges and opportunities, sharing lessons from successful and emerging approaches, and identifying the critical enablers for sustainable implementation and scale to inform actionable recommendations promoting equitable cancer care.