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The pace and complexity of today’s scientific opportunities demand financing models that are more collaborative and resilient than those that depend primarily on government funding. As demand for research talent grows, science R&D is being reshaped by new actors, new incentives, and new capital structures. How can public- and private-sector partners build financing models that keep high-impact R&D moving from early-stage discovery to translation and adoption? What partnerships, pooled vehicles, and incentive structures can support young scientists, sustain research capacity, and turn breakthroughs into real impact worldwide?