Climate change is emerging as the greatest health challenge of the 21st century, and its devastating impacts on human health and well-being are only accelerating, particularly amongst the world’s most vulnerable populations. Climate change is placing significant strains on global health-system infrastructure, increasing the demand for health services whilst also impairing the system’s ability to respond. Urgent action is needed to mitigate and adapt to this complex challenge and increased investment in resilient health systems must be made. This session is aimed toward developing cross-sector solutions, building global consensus for climate-health action, and investment in a healthier, more equitable future worldwide.