In the early weeks of 2020, the Milken Institute and The Harris Poll surveyed 23,000 people in 27 countries to identify their most urgent social and economic priorities. Then the pandemic hit. In the ensuing months, the Institute and Harris replicated the fieldwork to understand how people's pressing pre-COVID needs have been reprioritized in the midst of a pandemic. The results reveal that many of the challenges people face—including financial vulnerability, social injustice, and access to affordable healthcare—are both interdependent and amplified by the virus. This panel will explore how we can solve these most urgent challenges with renewed collaboration, innovative thinking, and tailored approaches to communities in need around the globe.