This annual gathering of leaders at the Global Conference will examine opportunities for accelerating advances in health across the healthcare continuum and throughout the lifespan. Advancing health requires fostering alignment and collaboration among the sectors that influence health, addressing areas where innovation and impact are needed (e.g., public health, food systems, biomedical research, treatment, technology and data, health financing and investments), and spreading solutions that lead to sustainable, equitable, and transformed systems. During this off-the-record session, health leaders will discuss barriers to resolve, lessons learned, and novel steps that can be taken to improve the health of people and communities in the US and around the world.