Building a Brand in Midlife: A Conversation with Daphne Oz and Molly Sims

After identifying a gap in the market for clinically backed skin care designed for women over 40, Molly Sims transformed a personal struggle with hyperpigmentation into YSE Beauty, one of the fastest-growing brands in the category. In conversation with Daphne Oz, Sims pulls back the curtain on what it actually takes to go from public figure to founder: navigating supply chains, structuring investor pitches, securing a Sephora partnership, and balancing the demands of company-building with family life—and why she considers it both the hardest and most meaningful work of her career.