Structural transformations in the global economy are opening a new window of opportunity to catalyze investment and deepen economic integration across the Americas. This session will examine new efforts to mobilize capital, strengthen critical supply chains, and foster sustainable development including the Americas Partnership for Prosperity, the Americas Act, and the BID for Americas initiative. Discussants will identify concrete steps to leverage public-private partnerships, multilateral institutions, and tools to translate this policy vision into tangible results—creating new opportunities for cross-border trade, investment, and inclusive growth.