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Artificial intelligence is opening up new possibilities for improving health at scale, from identifying risks and diagnosing disease earlier to accelerating drug discovery and enabling more personalized care. AI is also changing how health care is experienced, giving clinicians new tools to work more effectively and helping people better understand their own health. As these capabilities become more powerful, so does the opportunity to be intentional about where we direct them. Focusing AI on the problems and outcomes that matter most could dramatically expand its potential to improve health and longevity as well as help people live fuller, more productive lives. This private session will bring together leaders across sectors to define shared ambitions for the impact we want AI to have on human health and to consider how greater alignment could focus investment and action toward the areas with the greatest potential for impact.