People of all ages, ethnicities, and backgrounds endure the intense shifts in mood and energy levels bipolar disorder (BD) causes. Severe, repeated manic and depressive episodes can strain relationships, make it difficult to hold a job, and create a devastating ripple effect on people’s lives, making them feel like they are not in control.
Bipolar disorder affects roughly 3 percent of the world’s population. While BD is common, its cause is unknown, and because there are vast differences in how people experience bipolar disorder, it can take years to get the correct diagnosis. Like many other diseases, research for BD is underfunded, but there are ways philanthropic investments in the field can advance progress and improve our understanding of BD, and get to better interventions to help people regain control of their lives.
This Giving Smarter Guide by the Center for Strategic Philanthropy (CSP) builds on the Survey of Lived Experiences released in 2018. Here, CSP takes a detailed look at the BD research and funding landscape and makes recommendations for how philanthropy can advance the field.
Long before COVID-19 became a pandemic, America’s mental health system was failing to meet the needs of people requiring care. Today, more than 1 in 3 Americans report signs of clinical anxiety and depression—and in part because of the...
For many veterans and their families, the transition from military service to civilian life—the military-to-civilian transition (MCT)—can present practical, logistical, and emotional challenges that affect their ability to thrive post...
This Giving Smarter Guide describes the current state of research, clinical practice, and treatment approaches for uterine leiomyosarcoma (uLMS) and identifies critical areas where philanthropy can significantly advance scientific knowledge...
When most people think about advances in medicine, drug development is the first thing that comes to mind. However, technology and devices are proving to be valuable options for treating intractable illnesses. Technological solutions in the...
Fear, anxiety and social isolation brought on by the pandemic has exacerbated existing mental health challenges for people on college campuses, and created new ones as online learning expands, key rites of passage are cancelled, and social...
The Ann Theodore Foundation (ATF) is launching a new funding program to support the study of repurposed mechanistic target of rapamycin (mTOR) inhibitors as treatments for cutaneous sarcoidosis. This program will be executed in partnership...
February 20, 2026 (Washington, DC)—The Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), in partnership with the Ann Theodore Foundation (ATF), has launched a new funding program to support a future...
Schizophrenia is a serious, chronic brain disorder affecting about 24 million people worldwide. Individuals with schizophrenia experience a variety of symptoms—most notably psychosis—and face significant challenges accessing the care they...
The Ann Theodore Foundation, in partnership with the Milken Institute Science Philanthropy Accelerator for Research and Collaboration (SPARC), is accepting optional letters of intent through Thursday October 23, 2025, for its fifth round of...