Once viewed as a complex logistics system, the health-care supply chain has become a global hot topic. The health-care supply chain of today and tomorrow is being shaped and transformed by the necessity to meet changing demands, manage risks, and align with evolving societal and environmental concerns. Rapid advancement of technology may also create opportunities for a supply chain that accounts for future disruptions. How are digital platforms and AI reimagining the supply chain for the future? How can policy advance innovation while ensuring compliance and security protections of the supply chain? How has the demand for last-inch mile delivery reinventing health supply chain distribution and logistics? This session will discuss how end-to-end stakeholders across the health-care supply chain are leveraging innovation for future readiness and sustainable resilience to meet ever-evolving challenges of our complex world.