Health care is undergoing a transformation driven by digital innovation, new care models, and the shifting role of the employer. This transition to smart health ecosystems focuses on wellness, prevention, personalized care, and employers’ responsibility in helping their employees access these ecosystems and accompanying resources. Speakers will assess how advanced technologies—AI, mobile health applications, and telehealth—are delivering more personalized and preventive care encompassing a whole-person health approach. This session will highlight the need for public-private partnerships, appropriate regulations, and strategies to tackle broader health challenges such as pandemics and climate change, including their impacts on mental health. The panelists will address the critical questions of how to foster innovation, attract investment, and develop a future-ready health-care workforce.