Even as the world emerges from the COVID-19 pandemic, global supply chain disruptions are expected to continue for another year or two. Supply and demand mismatches, inventory and logistics bottlenecks, and regional geopolitical developments in Eastern Europe and the Asia-Pacific region have impacted global supply chain efficiency. Actions have been taken to boost supply-chain security, including investing in and building up domestic production capabilities. With supply-chain resilience and business security the growing focus of more companies and governments, how are the US and Asia's major industries responding? What opportunities and challenges do they face as they reconstitute business partners and supply chains?