Preventable illnesses remain a leading cause of death worldwide. Non-communicable diseases such as cardiovascular disease, diabetes, and obesity account for most premature deaths, fueled by limited access to healthy foods, inactivity, and inadequate screening. Socioeconomic disparities further limit access to preventive services; however, evidence shows that early detection and community-based interventions can reduce morbidity, mortality, and costs—underscoring that focusing on sick care alone is unsustainable.

Building on our long-standing efforts to advance preventative health and community-based biomedical research, the Milken Institute reviewed literature and engaged stakeholders through roundtables and workshops to identify evidence-based models for enhancing preventive services. This brief summarizes key findings, as well as principles and partnerships necessary to scale preventive service delivery.

As an immediate next step, Milken Institute Health has launched the Project Prevent Collaborative, convening stakeholders to finalize plans for statewide or national expansions. As a facilitator and champion, the Institute will connect funders, community organizations, and policymakers, promote prevention-first policies, share best practices, and spotlight success stories—driving preventive care toward a more sustainable health system.