Many COVID-19 survivors of all ages experience alarming neurological and physical signs and symptoms post-infection. Dementia-like symptoms, including memory loss and confusion—described as "brain fog"—are lingering burdens for some, while others confront an array of physical symptoms including shortness of breath, cough, and chronic fatigue. Several studies are in progress to investigate the impact of COVID-19, including a possibly increased risk of later-life cognitive decline or dementia. Researchers, clinicians, and health policy makers are striving to understand COVID-19's long-term impact as well as the supports needed by survivors and their families.