Antimicrobial resistance (AMR) continues to be a global threat, with significant human and economic consequences. Since 1991, this silent pandemic has caused over one million deaths annually, with total fatalities projected to rise to 39 million over the next 25 years. By 2030, AMR will cost the global economy up to $3.4 trillion yearly, and by 2050 it will have pushed 28 million people into poverty. Meanwhile, the antibiotic development pipeline continues to suffer from underinvestment and a lack of new treatments. However, emerging technologies—including artificial intelligence and advanced diagnostics—offer a promising lifeline. From accelerating drug discovery and improved diagnostics, to enhancing stewardship and surveillance, these new technologies have the potential to even the odds against AMR. Panel experts will discuss how cutting-edge technologies are transforming the fight against AMR—reducing its threat, saving lives, and mitigating its economic impact worldwide.