As the world gradually shifts from a unipolar toward a multipolar geopolitical order, the Global South is assuming a broader functional role across economic, diplomatic, and strategic arenas. Home to more than 60 percent of the world’s population, the Global South now accounts for one-third of PPP-adjusted global GDP. Annual Global South trade is projected to approach $14 trillion by 2033, with South-South trade expected to grow at 3.8 percent annually, outpacing the growth rate of North-North trade. From expanding intra-South investment networks to negotiating shifts in geopolitical alignments, the Global South is reshaping its position in the international system. In this session panelists will explore how these changes are redrawing the map of global trade, investment, and influence, and will hazard predictions on where the next wave of opportunity is likely to emerge.