Humanity's achievements over the last several centuries have been nothing short of extraordinary. More efficient and interconnected markets have animated a prolonged period of prosperity, peace, and stability. Advances in science and technology have pushed health, longevity, and connectivity, and have even enabled us to venture into the Cosmos. But this progress has come at a cost for which humanity is now paying: environmental degradation, geopolitical turmoil, economic inequalities, and global health pandemics. Where will these global trends lead in the future? How can humanity's prowess be realigned to heal a sickened planet? How can we ensure that future generations will be able to continue pushing above and beyond?