Over the past quarter century, the Milken Institute's FasterCures center has played a central role in accelerating medical solutions. It has created a new culture in the medical research community based on collaboration, patient activism, translational science and a sense of urgency. Institute Chairman Michael Milken moderates this panel of four executives who have led FasterCures and its predecessor organizations. As the world emerges from the COVID-19 pandemic, their optimism provides abundant hope for continued progress against all life-threatening diseases.