More than 7,000 diseases characterized as "rare" affect one in 10 people in the United States. A rare disease is one that affects fewer than 200,000 Americans at any given time. Although tremendous progress has been made in the last 30 years, more than 90 percent of rare diseases have no FDA-approved treatment. And even when treatments exist, delays in diagnosis can lead to unnecessary delays in treatment. What are the opportunities and challenges in providing faster delivery of diagnoses to patients and their families? How can advances in technology and data be leveraged to shorten the diagnostic odyssey?