Today, the line between clinical practice and clinical research is becoming blurred, largely thanks to investments in data, the existence of highly networked centers of excellence, and the work of research communities. Yet there is still much more to be achieved to create an optimal environment that ensures timely diagnoses and treatments. How can shared discoveries in the health system feed back to new discoveries in oncology? This private session will identify what has been effective in cancer care and what has not. Case studies on the most pressing barriers against and greatest learnings about other diseases also will be explored.