A global innovations race is underway. With humanity facing increasingly challenging crises—global warming, infectious and non-communicable diseases, lack of access to financial services and the formal economy, inability to participate in the real economy—companies and governments around the world are racing to incubate and scale the ideas that could solve these issues, and to take the lead in building back better. What are the biggest challenges today that will require the most creative solutions? What innovations are needed to ensure more people enjoy good health and well-being in the years ahead?