The health-care supply chain has undergone significant transformations driven by evolving health-care demands, technological advancements, and regulatory shifts. Patient-centric approaches, upskilled workers, and enhanced industry-wide collaboration are strengthening end-to-end resilience, enabling the fulfillment of patient needs on an unprecedented scale. This session will explore what may help accelerate transparency, communication, logistics and security to overcoming access challenges in under-resourced communities. The panelists will also discuss what may be achieved through digital enablement, industry readiness for the upcoming implementation of the Drug Supply Chain Security Act and potential actions to mitigate labor and drug shortages.